Latest technologies from Washington State University

Medium for Culture of Mammalian Cell Lines

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:43 GMT

Title: Interstitial Fluid-modeled Medium (IFmM) for Culture of Mammalian Cell Lines Unmet Need: Novel Interstitial Fluid Media to Mimic Physiological Condition There exists a need for a nutrient medium media that mimics the qualities of interstitial fluid to allow for growth of tissue cultures under physiological conditions similar to those in live models. Therefore, a need exists for a eukaryotic cell culture media to provide for nutrient compositions that are better suited to physiological base line conditions. The Technology: Novel Nutrient Media The technology relates to a n...

Novel Heat Exchanger for Staged Cryogenic Refrigerators

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:41 GMT

Unmet Need: Maximized efficiency of heat exchange Current sources of renewable energy such as solar power, windmills, and dams do not produce constant power outputs, and must be supplemented with nonrenewable sources of energy to prevent outages. Alternatively, storing excess energy produced by renewable resources would negate this concern. Hydrogen liquefiers powered by this excess energy could be used to generate renewable, energy dense hydrogen which could be stored and used on demand. However, hydrogen liquefiers operate at very low efficiencies, due in large part to the inefficient desi...

Soil Health Sensor

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:38 GMT

Unmet Need: Fast and accurate measurement of soil health Soil health is a complex phenomenon that reflects the ability of soil to support both plant growth and other ecosystem functions. Research on electron transfer processes in soil environments is limited and can provide novel knowledge and new ways of monitoring soil health. Electrochemical activities in the soil can be studied by inserting inert electrodes, and in turn these measurements can be used to determine soil health rapidly and requiring less expertise compared to current technologies. The Technology: Soil reactor to bette...

Environmentally Friendly Method for Recycling Plastic Waste

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:37 GMT

Unmet Need: Easy recycling of difficult to discard plastics Extensive use of plastics has led to waste disposal management difficulties and serious environmental problems such as intensive energy consumption, toxic gas emission, and occupying many landfills as synthetic plastics such as polyethylene terephthalate (PET) do not rust and are not easily degraded in an outdoor environment. Therefore, there is a need to provide a high-efficiency, low-energy consumption, and environmentally friendly recycling technology for PET plastic waste. PET plastic accounts for ~8% of the total waste p...

Additive Manufacturing of Ion Selective Membranes and Electrodes

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:29 GMT

Title: Ion Selective Membranes and Electrodes Unmet Need: Increased availability of specific membranes and electrodes Ion selective membranes and electrodes are ubiquitous in use and are a key component of diagnostics, research, and industry. However, improvements can be made to utilize ion selective membranes and electrodes using 3D/additive manufacturing. Through the use of such techniques there can be a reduction of fabrication time, a decrease in production cost, and an increase in use and production. The current technology allows for development of cost effective and specific ...

Treatment of Neurological and Inflammatory Conditions with Probiotics

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:25 GMT

Title: Treatment of neurological and inflammatory conditions with probiotics Unmet Need: Treatment of Neuroinflammatory Conditions Neuroinflammatory conditions lead to several ailments, including Acute Disseminated Encephalomyelitis (ADEM), Acute Optic Neuritis (AON), Transverse Myelitis, Neuromyelitis Optica (NMO), and Multiple Sclerosis (MS). Neuroinflammatory diseases are generally treated with several treatment methodologies include medicinal drugs, however new pharmaceutical free treatment options are needed in addition to traditional treatments. This technology addresses a ne...

MICRONEEDLE ARRAY WITH A CONTROLLABLE LOCKING FEATURE

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:15 GMT

Unmet Need: Easy fixation and removal of microneedle for drug delivery Microneedle (MN) arrays are medical devices used to deliver drugs to the human body via bypassing the skin barrier, namely the stratum corneum. Given MNs’ small size, they provide a less painful and minimally invasive approach to delivering via the skin. One challenge for using MNs for drug delivery is the fixation and removal of the MN. Existing methods, such as using an adhesive backing, face issues including scarring and tissue damage, limited adhesion, and complicate the manufacturing and application proces...

Ti-Ta-Cu alloys for Implants

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:14 GMT

Title: ALLOYS AND METHODS FOR BIOLOGICAL IMPLANTS Unmet Need: Improved production methods and alloy materials for biological implants. The growing need for implants is increasing with an aging national population, and an increase in the use of implants to treat a younger and younger range of patients. With the increased need for implants there is also a need for higher strength and affordable implants that resist bacterial growth, while promoting bone adhesion. Through the use of 3-Dimensional printing and other forms of additive manufacturing custom implants can be made of high st...

Neutrophil Apoptosis induced by Nanoparticles Improved the Therapies of Inflammatory Diseases

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:11 GMT

Title: Neutrophil Apoptosis induced by Nanoparticles Improved the Therapies of Inflammatory Diseases Unmet Need: Improved specific induction of neutrophil apoptosis through the use of nanoparticles to treat inflammatory diseases. Systemic inflammatory responses are a normal response to infections and tissue damage, however when the expression of inflammatory cells is uncontrolled associated diseases occur. Through specific targeting of neutrophil by the current technology a return to homeostatic levels of neutrophils can be accomplished. This neutrophil apoptosis inducing drug how...

CANVASS: Cyber Attacks and Network Vulnerability Analytics Software for Smart Grid

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:07 GMT

Unmet Need: Contingency preparation and management Quantifying the resiliency of power transmission and distribution networks is essential to determine and devise suitable control mechanisms to minimize the effects of undesirable events in the power grid. Existing management practices can handle reliability and restoration and reliability in response to isolated faults of one to two critical infrastructure components (N-1 or N-2 contingencies). No industrial software today is capable of analysis beyond N-2 contingencies. The Technology: Software tools for power grid cyberatta...

CP-TRAM: Cyber-Physical Transmission Resiliency Assessment and Management

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:24:05 GMT

Interactive Therapeutic Booth with Real-time Emotional Monitoring to Improve Mental Health and Well-being

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:59 GMT

Challenge: Automated emotional recognition and environmental adaptationMental health challenges such as post-traumatic stress, autism spectrum disorders, and aging-related cognitive decline are difficult to treat, and access to trained therapists is limited. Existing sleep and meditation pods can sooth healthy individuals, but are not capable of recognizing and adapting to emotional responses. The Technology: Interactive Emotive SpacesEmotive booths, kiosks, and other adaptive structures interact with individual users by deriving a perceived emotional state associated with physiolog...

Production of composite wood-strand panels for construction applications

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:54 GMT

Unmet Need: Improved production methods and enhanced performance and longevity of construction wood A challenge with current thin, wood-based construction panels is their performance and longevity when exposed to high moisture environments. Moisture infiltration and accumulation over time, poor maintenance, window and roof leaks, or condensation and plumbing leaks can render these products susceptible to biodegradation due to fungal decay or deformations such as cupping and warping, leading to performance degradation and undesirable visual defects. The Technology: Thermally modifying comp...

Grid Control for Unknown Resonance Events (CURE)

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:51 GMT

Unmet Need: Detection and damping of resonance events in a power gridComplex electric distribution systems cannot be perfectly modeled to reflect every duty cycle and configuration of each component which might come on-line. Recent instances of forced oscillations in wide area networks illustrate the difficulty in quickly locating their causes, and the danger of widespread service disruptions. Along with ongoing research aimed at speedy localization and targeted disconnects, operators and power users can benefit from active measures aimed at stopping forced oscillations of unknown ...

Production of lignin with controlled structural properties

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:49 GMT

Unmet Need: Production of high-performance composite materials using lignin The emerging biomass refinery industry generates an enormous amount of lignin as waste in biochemical biomass-to-biofuel conversion processes. No practical biorefinery lignin valorization process has been demonstrated so far. Given the potential volume of biorefinery lignin, diverting the majority for material production is a particularly appealing approach. Unfortunately, existing technologies cannot produce high-performance composite such as carbon fiber using lignin. The key to solving this technical challenge is t...

GPU-ReRAM Heterogeneous Architecture for Machine Learning

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:45 GMT

Unmet Need: Efficient architecture for employing Deep Neural NetworksDeep Neural Networks (DNNs) employed for image segmentation are computationally more expensive and complex compared to the ones used for classification. GPU-based platforms are the most popular choice of hardware for training DNNs but are not specifically optimized for this task. Resistive Random-Access Memory (ReRAM)-based architectures offer a promising alternative to GPUs. However, due to their low-precision storage capability, these architectures cannot support all DNN layers and suffer from accuracy loss of t...

Time-based Circuits and Systems for Wideband Spatial Signal Processing

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:43 GMT

Unmet Need: Competent spatial signal processing for large modulated bandwidthsNext-generation phased-array systems with large modulated bandwidths and high energy efficiency will enable wireless communication at the speed of Gigabyte/second such as in 5G communications. The state-of-the-art phase-shifter based arrays and true-time-delay based spatial signal processing at this large scale cause unsolved challenges such as beam-nulling with a swept single tone in a baseband to radio-frequency (RF) impedance translation, frequency-dependent filtering for applications at lower RF carrier frequenci...

Network Silica strengthened bonding of Fiber Composites

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:42 GMT

Unmet Need: Enhanced bonding performance between fiber composites and cementitious mixture Corrosion of steel reinforcing bar (rebar) limits the life of rigid concrete structures. Steel is still widely used due to low cost, but alternative fiber reinforced polymer (FRP) rebar is now available and offers numerous advantages including low weight and thermal conductivity. FRP also has higher tensile strength, which only provides benefit if matched by high bond strength between the FRP and concrete in which it is embedded. The Technology: Addition of networked silica to bonding surf...

Pneumatic spray delivery reservoir

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:38 GMT

Challenge: Pressure drop in fixed sprayers for high density trellised orchardsFarmers are pursuing increased crop density in orchards using trellised trees. Existing irrigation and agrochemical applicators are not optimized for such orchards. Challenges with mobile pesticide sprayers include operators’ proximity to concentrated chemicals, excess resource use, and narrow operating conditions. Fixed plumbed sprayers known as solid set canopy delivery systems (SSCDS) provide benefits over mobile sprayers for higher density crops, but existing hydraulic spray delivery (HSD)...

The Professional Handbook of Cider Tasting

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:35 GMT

The Professional Handbook of Cider TastingUnmet Need: Standardized Guide for effective sensory evaluation of Cider in the US.In the last decade, with the rise of the craft beverage movement, the cider industry has experienced an annualized growth rate of 27.3 % reaching $300.4 million in revenue from 2012 to 2016. For the next five years, cider sales are projected to continue growing at a more sustainable rate of 1.2%. In the midst of the industry's rapid growth in the U.S., there are insufficient publications for understanding both the theory and practice of effectively evaluating the sensory...

One-step one-pot synthesis of aliphatic amine and nitriles

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:33 GMT

Unmet Need: Single-step synthesis of aliphatic amine and nitriles With a growing market of high-quality surfactant and emulsifiers, global demand for amine and nitriles is growing rapidly. Traditionally, aliphatic amine are synthesized in multi-step process that treat feeds of multiple components like alcohols, olefin, nitriles etc. Current synthesis routes employed to produce aliphatic amine and nitriles have drawbacks like use of expensive reagents, multi-step process, formation of toxic by-products and poor selectivity to primary amine and nitriles. The Technology: Nitrogen func...

Gradient Alloyed Metal Oxide Photovoltaics

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:30 GMT

Challenge: Use of copper oxide as a semiconductor in solar cells promises to reduce fabrication and material cost of photovoltaics. Despite this, the highest reported actual energy conversion efficiency is less than 5%, and as such is not yet competitive on the market for most applications as compared to existing silicon-based cells. Technology: This technology employs low-cost electrodeposition of metal oxide films and boosts solar energy conversion efficiency by interdiffusing metal oxide layers at the p-n junction to form multiple gradient bandgap structures without d...

Renewable agro-based deicers for winter roads

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:29 GMT

Unmet Need: Bio-based sustainable winter road maintenance operations The United States alone spends approximately $2.3 billion each year to keep highways free of snow and ice. The highway winter maintenance operations which primarily use chloride salts cause considerable damages to infrastructure, motor vehicles and the natural environment and add at least $5 billion to this cost. Recent studies have explored usage of bio-based deicers. However, there are gaps in these studies related to the materials and unknown compounds including raw bio-based materials, waste of industrial processes and co...

Origami structure as an expulsion bladder for a rocket tank

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:26 GMT

Challenge: Supply of vapor-free cryogenic liquid propellant in a rocket tank The key to propellant transfer in microgravity is the propellant management device (PMD), which ensures that vapor-free propellant is supplied from a source tank (e.g. a fuel depot) to a receiver tank or engine. Failure to do so for engines will result in combustion inefficiencies and even engine failure. Most traditional surface-tension based PMDs face difficulties when handling cryogenic liquids, and thus primarily occupy low-to-mid technology readiness levels (TRLs). Bladders are an attractive alternative to surfa...

Fuel Cell and Electrolyzer Hotbox Modules Using Conductive Zirconia Stacks

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:17 GMT

Unmet Need: Durable materials for pressurized fuel cell cores Solid oxide fuel and electrolyzing cells present harsh oxidizing environments for materials due to fuel reactions and the high temperatures required for efficient operations. Metal anodes are subject to coking and delamination, and measures to reduce degradation include use of costly coatings and alloys which continue to break down under pressure. The Technology: Fabrication method for conductive zirconia hotbox stacks This enables modular pressurized hotboxes for use in fuel cells, reversible solid o...

Software Application for Crop and Pest Management in Africa

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:15 GMT

Challenge: Update farmers about emerging management techniques and pest controlFarmers in Africa are sometimes uninformed on modern farm practices and technologies. Language and literacy challenges make it difficult to spread information on pests and the results of academic research. Existing information tools often rely on active internet access and reading skills, leaving farmers behind and food production stunted.The Technology: A software application acting as virtual assistant to farmersResearchers at WSU present an audio-visual mobile application called CornBot.&n...

Bacterially secreted immunostimulants to protect plants against pathogens

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:11 GMT

Unmet Need: Effective strategies to protect plants from root knot nematodeRoot-knot nematodes (RKN, Meloidogyne spp.) are major agricultural pests on a global scale and can cause billions of dollars in yield loses each year. The temperate root-knot nematode Meloidogyne chitwoodi is endemic to the potato growing regions of the Pacific Northwest of the USA, as well as areas of Europe, Asia, and Africa. This species is important in potato production because it can infect the tubers, causing unsightly galling and brown spots to form under the tuber skin. Commercially available potato cultivars do ...

Biphasic catalytic upgrading of vegetable and cooking oils and animal fats to jet fuels

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:09 GMT

Unmet Need: Single-step efficient, cost-effective process for bio-jet fuel generationBiomass is one of the biggest contributors of renewable energy. Current methods for production of bio-jet fuel from biomass include multiple pathways which include complicated processes for renewable jet process, catalytic process and pyrolysis. Notwithstanding the high yield of jet fuel, the complicated process increases the operating cost in the aviation industry. Existing single step processes are inhibited by low yield and poor deoxygenation rate, require high reaction temperature and hydrogen pressure inc...

Conversion of co-mingled waste plastics to monomers and fuels

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:07 GMT

Unmet Need: Better management and utilization of waste plastic accumulated in landfillsHuge amounts of plastics is produced every year and es expected to double over the next two decades. A vast majority of waste plastic is accumulated in landfills sloughing off in the natural environment as litter. The degradation of plastic polymers in landfill may take hundreds of years. The waste accumulated eventually ends up in oceans and has resulted in an ecological crisis. This waste poses a threat to marine and freshwater organisms and humans. These reasons make it imperative to develop alterna...

Wheat Variety 'Stingray CL+' (WA8275), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:23:04 GMT

Stingray CL+ (WA8275CL+) is a soft white winter wheat with 2-gene resistance to the herbicide Imazamox, developed and released in 2019 by the Agricultural Research Center of Washington State University. Stingray CL+ has excellent resistance to Imazamox herbicide applications under recommended label rates. This cultivar provides a combination of broad adaptability, excellent grain yield potential, high test weight, good end-use quality, and disease resistance. Stingray CL+is adapted to the broad dryland production regions of Washington and Northern Oregon. The excellent agronomic and dise...

Deep neural network a posteriori probability detector for magnetic recording

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:59 GMT

Unmet Need: Multi-track detection for two dimensional magnetic recordingHard disk drives (HDDs) shipped currently use one-dimensional (1D) perpendicular magnetic recording. HDD industry is approaching an areal density limit for conventional 1D magnetic recording. HDDs store only binary data, hence equalization techniques such as OFDM are not suited. HDD recording channels have media noise. Currently trellis based Viterbi algorithm (VA) is used to detect coded data bits in presence of ISI and media noise. Two-dimensional magnetic recording suffer complexity with VA and it grows exponentially wi...

Bio-electrochemical Wastewater Treatment System

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:57 GMT

Unmet Need: Effective strategies for wastewater treatment.The treatment of municipal wastewater is an energy intensive process, with the delivery of oxygen as a soluble electron acceptor accounting a significant share of the total energy consumption. There is a need to find low-cost effective ways of wastewater treatment.The Technology: Switchable dual-mode wastewater treatment system.Earlier, Microbial fuel cells (MFC) have been proposed as a solution to reduce energy requirements but they can demonstrate power generation only under defined conditions. Researchers at WSU have developed ...

Wheat Variety 'Net CL+' (WA8280), Hard Red Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:56 GMT

Net CL+ is a broadly-adapted hard red spring wheat with two-gene tolerance to BeyondTM herbicide for use in rotation in ClearfieldTM production systems in all production zones of the Pacific Northwest. It has an excellent yield record, with above average grain protein, good adult resistance to stripe rust, medium height with very good straw strength, very good test weight, and Hessian fly resistance in low, intermediate, high rainfall production areas. Net CL+ combines top-end yield potential, high test weight, and above average grain protein compared to most hard red spring wheat variet...

Package-mounted Colorimetric Freshness Sensors for Pasteurized Milk

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:54 GMT

Challenge: Waste of Milk in Cold ChainLifespan of pasteurized milk and other perishables varies greatly based on temperature control throughout the refrigerated distribution chain. Production date is a poor proxy for freshness; batch marking of dates at initial processing does not allow for fine distribution management controls or consumer confidence that product is always fresh before marked dates. In ideal conditions, milk may be safe and fresh-tasting beyond the expiry date, but dumped by grocers at that time. More often, temperature abuse results in spoiled product ...

Strong ultralight foams based on nanocrystalline cellulose for high-performance insulation

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:53 GMT

Unmet Need: Energy efficient and renewable insulation materials. Thermal insulation materials play a vital role in energy preservation in buildings and construction, transportation, and packaging industries. Expanded polystyrene has been widely used for commercial lightweight, high thermal conductivity insulation. However, it is petroleum-based, composed of toxic styrene blocks, and exhibits relatively poor fire resistance with substantial tail ash floating in the air after burning. It therefore poses the risk of environmental contamination and health side effects. In addition, polystyrene doe...

Generating Ammonia Excreting Mutant Bacterial Strains

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:51 GMT

Generating Ammonia Excreting Mutant Bacterial StrainsUnmet Need: Effective Nitrogen-fixing Symbioses of Non-Legumes.Legumes have been an integral part of sustainable agricultural systems for thousands of years due to their ability to form nitrogen fixing symbioses with diazotrophic bacteria. Unfortunately, many important food species including the grasses, maize/corn, rice, and wheat cannot establish effective nitrogen-fixing symbioses with diazotrophs, which means that they are largely dependent on nitrogenous fertilizers to increase yields. The Technology: Creation of Ammonia Excreting ...

Size-Adjustable Functional Maternity Hospital Gowns

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:49 GMT

Unmet Need: Comfortable maternity Hospital Gowns.Labor and delivery are important markets in healthcare and there is increasing demand for quality maternal health services. There is particular interest in the availability of functional, comfortable, and aesthetically pleasing maternity hospital gowns. According to a survey of over 500 postpartum women conducted by WSU faculty member Dr. Chanmi Hwang, currently available gowns are considered uncomfortable and in great need of improvement. Providing superior hospital gown options for women would greatly improve patient experience, comfort, and w...

A Method For Assessing Neurodevelopmental Abnormalities

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:47 GMT

Unmet Need: Technology to assist in clinical screening of neurodevelopmental abnormalities. There has been research to support clinical screening of neurodevelopmental disorders particularly ASD. The current technologies capture pupils, but does little to guide the user towards capturing the measurement in children. Also, it does not provide a comparative measure for interpretation in relation to developmental of the pupillary light reflex response/visual pathway over time. The Technology: Using pupillary light reflex measure to detect neurodevelopmental abnormalities. Proposed technolog...

Fungus for control of Varroa mites in Honeybees

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:43 GMT

Unmet Need: Effective controlling agents for Varroa mitesVarroa mites are a devastating parasite considered the top driver of honey bee colony losses over the past several decades. Products for varroa control are desperately needed. The general idea of using entomopathogenic fungi to control Varroa mites had been explored previously. However, none of the available fungal strains performed well enough to become commercially viable. The Technology: Use of Metarhizium brunneum as the controlling agent. Researchers at WSU have deve...

Identification of Cats at a High Risk for Developing Chronic Kidney Disease

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:41 GMT

Unmet Need: Effective strategies to identify cats that will benefit from early intervention to prevent onset of CKDChronic Kidney Disease (CKD) is the most common metabolic disease of domesticated cats and a clinically important cause of mortality in aged domestic cats. Despite the high prevalence of kidney disease, the underlying reasons why some cats are remarkably prone to this disease are still unknown. Availability of a method to identify cats at a high risk to develop CKD would allow for early intervention through dietary and lifestyle changes and could greatly improve a cat’...

Host-free culture medium for ‘Candidatus Liberibacter asiaticus’

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:29 GMT

Host-free culture medium for ‘Candidatus Liberibacter asiaticus’ Unmet Need: Effective strategies to cure Huanglongbing (HLB)HLB, also known as citrus greening disease, is an extremely destructive disease of citrus trees. The disease is a great threat to the citrus industry. Currently, three species of ‘Candidatus Liberibacter’ have been described as main cause of HLB. Among them, ‘Candidatus Liberibacter asiaticus’ (C.L. asiaticus) has been described to be a major threat for America’s citrus industry. It is critical to obtain a host-free cu...

Trackable, implantable medical device for diagnostic data delivery.

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:27 GMT

Unmet Need: Accurate and efficient wireless communication with instrument in human body. Minimally invasive catheter based endovascular and intracardiac procedures play an increasingly critical role in modern medicine and are used to treat a wide array of medical conditions encompassing the clinical fields of interventional radiology (IR), cardiology (CC) and electrophysiology (EP). Instrument tracking or navigation capabilities and ability to deliver therapy and retrieve diagnostic information are essential components required for this technology. The Technology: System and method of wireless...

Renewable Energy Storage via Efficient Reversible Hydrogenation of Piperidine captured Carbon Dioxide

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:20 GMT

Unmet Need: Using heterogeneous catalysts for hydrogen storageThe worldwide installed solar photovoltaic (PV) and wind energy capacity have surged exponentially for the past decades.1 However, renewable power generation is highly intermittent and seasonal, resulting in serious issues including grid capacity/stability, curtailment, and supply/demand mismatch. The storage of renewable energy is the major hurdle during the transition of fossil resources to renewable energy. One possible solution to the storage challenge is to use a regenerative hydrogen fuel cell (RHFC), which converts elec...

Anti-inflammatory activity by Doxorubicin-Conjugated Nanoparticles

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:18 GMT

Unmet Need: Effective therapy for inflammatory disorders. Inflammation is a key physiological response to bacterial and viral infections. Neutrophils are an important part of the innate immune response and normally maintain a constant population by undergoing spontaneous apoptosis after a short lifespan of 8-20 hours. However, it is well known that neutrophils display exaggerated activation and inefficient clearance in response to insults such as microorganisms and damaged cells. This results in excessive inflammation that can contribute significantly to pathology. ...

Baking-Stable Red Raspberries

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:22:15 GMT

Challenge: Frozen raspberries break down and bleed in mixing and bakingWhole blueberries are commonly found in commercial baked goods, and strawberries are often mixed into ice cream. Raspberries preserved by traditional methods are not similarly hardy and suited to various applications, exhibiting high levels of lysis and syneresis when mixed or thawed. This Technology: Stabilized frozen produceWSU has developed a new process of stabilizing and preserving produce which combines vacuum infusing, dehydrating, coating, and freezing to create a premium value-added product, ...

Biobased Epoxy Resins and Curing Agents using Rosin Acids as Building Blocks

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:50 GMT

Abstract WSU inventors have developed epoxy resin systems and carboxylic terminated polyesters using rosin acids as building blocks. This provides a method to make epoxy resin systems that do not contain Bisphenol A (BPA). Current powder coating polyester resins are built largely on tere-or isophthalic acid and trimellitic anhydride as rigid monomers together with other reactants. The epoxy resin is either diglycidyl ethers of bisphenol A or epoxy-novolac resin, both are based on the phenol building block. Rosin and derivative as adhesive tackifier is a well-established practice, and they have...

Synthesis of Mesoporous Calcium Silicate for Controlled Release of Protein or Drug

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:47 GMT

Abstract This WSU invention relates to mesoporous calcium silicate compositions and methods for producing mesoporous calcium silicate for controlled release of bioactive agents. Bioactive agents can include protein growth factors, pharmaceutical drugs, antibiotics, antimicrobial agents, and polypeptides just to name a few potential agents. With this technologies, novel method of controlled release coupled with the pluripotency of available bioactive agent, make it so this technology has multiple applications. The mesoporous calcium silicate is modified via acid to generate calcium silicate par...

The UQCRC1 Promoter Polymorphisms with High Expression Activity Increase Muscle Lipid Accumulation & Subcutaneous Fat Depth

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:43 GMT

Significant improvements in animal performance, efficiency and carcass and meat quality have been made over the years through the application of standard animal breeding and selection techniques. However, such classical animal breeding techniques require several years of genetic evaluation of performance records on individual animals and their relatives and are therefore very expensive. Other efforts have been made to improve productivity and quality through the application of such management practices as the use of feed additives, animal hormonal implants and chemotherapeutics. However, there...

Urotensin 2 and its Receptor as Candidate Genes for Beef Marbling Score and Subcutaneous Fat Depth

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:39 GMT

Resorbable Ceramics with Controlled Strength Loss Rates

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:32 GMT

Abstract The WSU researchers have developed calcium phosphate-based resorbable ceramics with select dopants, optimized for in vitro degradation and cell-materials interactions as a function of time. This technology is an advanced resorbable biomaterial that allows for quicker restoration of functionally loaded natural bone. This synthetic calcium phosphates demonstrates properties similar to natural bone, but they lack the mineral content inherent to bone. This novel ceramic based calcium phosphates with different dopants allows for a number of applications but the most prominent is in c...

FABP4 Gene Markers for Marbling and Backfat in Beef Cattle

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:26 GMT

Abstract Significant improvements in animal performance, efficiency and carcass and meat quality have been made over the years through the application of standard animal breeding and selection techniques. However, such classical animal breeding techniques require several years of genetic evaluation of performance records on individual animals and their relatives and are therefore very expensive. Other efforts have been made to improve productivity and quality through the application of such management practices as the use of feed additives, animal hormonal implants and chemotherapeutics. How...

TFAM Gene Markers Marbling and Backfat in Beef Cattle

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:18:22 GMT

Biopsy Needle

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:46 GMT

Unmet Need: High efficiency Biopsy DevicesBiopsy procedures are widely used for cancer diagnosis and monitoring. Out of currently available biopsy techniques, surgical biopsy is most accurate but it is highly invasive and expensive. The other techniques like fine needle aspiration (FNA) cytology and core needle biopsy (CNB) are less invasive but have their own limitations. There is a need to find a Biopsy technique which is efficient and yet less invasive.The Technology: Novel Biopsy Needle Researchers at Washington State University’s School of Mechanical and Materials Engineering have d...

Production of Complex Flavonoids

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:45 GMT

Unmet Need: Production of lipophilic methoxylated flavonoids Numerous methoxylated flavonoids exhibit pronounced bioactivities. Their biotechnological production and diversification are therefore of interest to pharmaceutical and nutraceutical industries. Efforts to engineer flavonoid mechanisms have been conducted earlier but there has not been much progress in production of lipophilic (poly) methoxylated flavonoids The Technology: Engineering yeast cells for production of methoxylated flavonoids Researchers at WSU selected a set of enzymes to construct five yeast strains that produce 8- ...

Sampled time delay based multi input multi output baseband receiver

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:43 GMT

Unmet Need: Wideband interference cancellation for wide modulated bandwidth The announcement on opening mm-wave bands for 5G by the Federal Communications Commission has intensified research in academia and industry on commercial mobile networks using mm-wave multi input multi output (MIMO) supporting wide channel bandwidths. However, as next-generation networks progress towards ultra-dense small cells, the dramatic shortening of inter-cell distances will result in both line-of-sight and non-line of-sight interference channels. While interference mitigation using electronic phased-arrays has b...

Low Cost and High Performance Transition-Metal-Based Electrocatalysts for Water Splitting

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:40 GMT

Unmet Need : Accommodating the unpredictable and intermittent nature of renewable energy requires efficient energy storage and conversion devices. One of the most promising solutions is to convert renewably generated electricity into fuels, such as hydrogen, methane, and ethanol. Electrolysis of water is considered an easy and clean method to obtain hydrogen. Oxygen evolution reaction (OER), however, as one of the two important reactions (hydrogen evolution reaction as the other part) involved in electrolysis, is the bottleneck for practical water splitting applications. The sluggish kinetics ...

Methods and Compositions for Prevention and Treatment of Apicomplexan Infections

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:37 GMT

Unmet Need: Effective treatment options to combat Apicomplexan parasitic infectionsDiseases caused by apicomplexan parasites, such as cryptosporidiosis and malaria are among the most devastating to humans and their domestic animals. Ongoing discovery and development of new drugs to treat these diseases is a medical and veterinary imperative. For example, cryptosporidiosis causes severe diarrheal disease in young children world-wide and is a major challenge to the beef and dairy industries as a primary cause of neonatal calf diarrhea, yet to date there are no drugs to control this i...

Wheat Variety 'Purl' (WA8234), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:34 GMT

Purl (WA8234) is a soft white winter wheat developed and released in 2018 by the Agricultural Research Center of Washington State University. Purl provides a combination of excellent yield potential, high test weight, good end-use quality, and disease resistance. Purl is best adapted to the intermediate to high rainfall dryland production regions of the inland Pacific Northwest. The unique disease resistance package and high yield potential of Purl makes it an ideal cultivar for growers looking to minimize risk and maximize profit on their farms.

Carbon-rich micro-particles for protecting bees and overcoming colony collapse disorder (CCD)

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:30 GMT

Unmet Need: Protection of honeybees from the effects of pesticides. The total economic value of honey bee pollination worldwide has been estimated to be around 10% of the global food production. Pesticides are a serious hazard to the honey bee industry, contributing to recent declines in honey bee colonies. The health of a honeybee has harmful effects after consumption of contaminated nectar or exposure to pesticides and/or other chemicals. At sub-lethal levels of pesticides, for example, honeybees develop abnormal behavior, foraging failure, and abnormal physiology, which negatively impacts t...

Cost-Effective Single-Step Process for the Catalytic Conversion of Methane to Methanol/Formaldehyde

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:28 GMT

Unmet Need: Currently there is no technology available in the market capable of producing Dimethyl Ether (DME) from methane in a single reactor. DME is an attractive substitute for diesel due to its high cetane number, which is a measure of its ignitibility in compression ignition engines. In addition, DME’s quiet combustion and inability to form harmful particulate carbon matter make it suitable for high-efficiency diesel cycle engines. The industrial-scale production of DME requires a network of pipelines to introduce CH4 into the process. In remote areas, where no gas grid is a...

Method of Detecting Sexually Transmitted Infections

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:26 GMT

Unmet Need: Effective strategy for rapid, accurate diagnosis of Trichomonas infections.Sexually transmitted infections (STIs) are a major global cause of acute illness, infertility, long term disability and death. Trichomonas vaginalis is now the number one non-viral agent responsible for sexually transmitted infections (STI). Trichomonas infections cause vaginitis in women and can result in infertility, cervical cancer and pregnancy complications. In men, infection has been associated with an elevated risk of prostate cancer. Although infection in men can manifest as non-gon...

Masonry Blocks using Recycled Gypsum Wallboard

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:25 GMT

Unmet Need: New use for construction & demolition gypsum drywallConstruction of an average 2000 square foot home produces more than a ton of gypsum wallboard waste. Gypsum wallboard waste is a low-value material, typically disposed of in landfills. Landfill disposal presents a significant problem due to anaerobic soil bacteria consuming gypsum and producing hydrogen sulphide (“rotten-egg”) gas, which is toxic in high concentrations. Furthermore, some landfills no longer accept gypsum wallboard waste.The Technology: Masonry blocks using recycled gypsum wallboardResearchers at Wa...

System for a Low Cost, High Fidelity Veterinary Simulation and Related Methods

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:23 GMT

Unmet Need: Teaching veterinary operative techniques in a low-risk environment Various learning methods are required to increase veterinary students’ comfort with surgical procedures before they work on live animals. Experiencing surgical procedures in a low-risk setting before performing a procedure in a real-life situation is very beneficial to the students. Recent studies have proposed the use of a simulation skills lab to address this need. This approach would promote the health and wellbeing of animals by reducing the need to use live animals to practice surgery in veterinary teachi...

Post-consumer Cotton Waste Recycling for High-Quality Brand New Fibers

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:17 GMT

Unmet Need: Efficient use of textile waste The worldwide fiber consumption for consumer textile products has been growing steadily in the past several decades due to population growth and living standard improvement. Given the fact that only about 15% of the post-consumer textiles are recycled, the number of textiles that contribute to the municipal solid waste (MSW) increases accordingly. Statistics from EPA shows every American adult averagely abandons 31 kilograms (i.e., 68 pounds) textiles each year, which account for 5% of MSW. Approximately two-thirds by weight of the textile wastes are ...

Wheat Variety 'Pritchett' (4J071366-1), Winter Club Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:14 GMT

Pritchett, a winter club wheat developed by Washington State University and the USDA-ARS, is targeted to the traditional low-intermediate rainfall club wheat growing region. Pritchett was named in honor of John Pritchett, who served the USDA-ARS wheat breeding program from 1957–2000. Pritchett has excellent emergence from deep sowing, excellent club wheat quality, and excellent resistance to stripe rust and Cephalosporium stripe disease. Pritchett should replace Bruehl in low rainfall areas due to superior yield, test weight, milling quality, eyespot tolerance, earlier maturit...

Cellulose Dispersions for Reducing Cold Damage in Tree Fruit

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:12 GMT

Unmet Need: More cost-effective and less labor-intensive cold damage protection technologyEconomic loss from cold damage is one of the most prevalent recurring production issues in temperate fruit industry, and poses a significant challenge to profitable and sustainable production. Each year, the U.S. produces >15M tons of deciduous fruit crops that have a combined value of >$11B. These crops are susceptible to cold damage, and the effects of unpredictable/unseasonable cold are a major threat to the profitability of the industry.The current methods of cold damage protection are undesirab...

Smartphone App for automated in-tree crop load estimation of apples

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:09 GMT

AbstractCrop-load or yield estimation is an important management tool for growers of fresh market fruit crops such as apples. Estimation of expected harvest volume is crucial for efficient management of pre- and post-harvest operations such as acquiring desired equipment and labor force for harvesting and transporting fruit from orchards to packing houses. There are no commercial equipment or platform that can automatically estimate the total number of fruit and fruit size in orchards. Washington State, which is the top producer and supplier of apples in the United States, produces 15-18 billi...

Enzyme-Directed Pro-lmmunostimulants for Cancer Therapy

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:07 GMT

Targeting of pro-immunostimulants to tumor environments Cancer treatments could be optimized through more effective ways of targeting immunostimulants to tumor environments. Current immunotherapies are limited to direct intra-tumoural infusion, due to severe inflammatory toxicity that results from systemic routes of administration. Directed Enzyme Prodrug Therapy (DEPT) is an approach that couples a drug with a substrate, together the prodrug, where the drug is not active until the substrate has been cleaved off. A DEPT approach for the delivery of an i...

Barley Variety 'Survivor' (07M-203), Two-row Spring Barley

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:17:05 GMT

Survivor is a two-row, hulled, spring feed barley developed by the Agricultural Research Center of Washington State University. Survivor is the first barley variety in the U.S. that possesses tolerance to IMI-herbicides in a high yielding genetic background. Survivor is adapted across all rainfall zones in dryland farming systems in eastern Washington. It is moderately resistant to stripe rust and has high protein and test weight in the feed barley market class. Survivor is not intended to be sprayed with IMI herbicides; rather it was developed to withstand residual herbicides in th...

3D tissue matrix scaffold for tumor modeling, biomarker/drug screening and tissue regeneration

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:58 GMT

Unmet Need: Lack of tissue culture models that resemble native microenvironmentMammalian extracellular matrix (ECM) is comprised of a labyrinth of interconnected architecture that provides mechanical support and optimal tissue microenvironment for cell survival, growth, signal transduction and interactions. The currently available scaffold and planar tissue culture models using synthetic polymers or a single component of ECM do not resemble this native living microenvironment. Therapeutic studies and preclinical applications based on these methods have failed to provide consistent data and acc...

Wheat Variety 'Sequoia' (WA8180), Hard Red Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:55 GMT

Sequoia (WA8180) is a hard red winter wheat developed and released in 2015 by the Agricultural Research Center of Washington State University. Sequoia provides a combination of superior emergence, excellent yield potential, and desirable end-use quality for dryland winter wheat production areas in the Inland Pacific Northwest. Data indicate Sequoia emerges faster than comparison varieties such as Finley and Farnum. Sequoia is best adapted for regions in Washington and Oregon receiving less than 12 inches average annual precipitation in a deep-furrow planting system, where the varieties F...

Wheat Variety 'Tekoa' (WA8189), Soft White Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:53 GMT

Tekoa has top-end yield potential, combined with desirable yield protection traits, and excellent quality. Tekoa is a soft white spring wheat variety released by Washington State University that may be grown in all production zones of the Pacific Northwest. It has later maturity, very good resistance to stripe rust, medium height with very good straw strength, very good test weight, Hessian fly resistance, aluminum tolerance, and excellent yield potential in low, intermediate, high rainfall, and irrigated production areas. As a later maturity variety with high test weight, it may provide...

Wheat Variety 'Ryan' (WA8214), Soft White Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:50 GMT

Ryan is a broadly-adapted soft white spring wheat released in 2016 by Washington State University that may be grown in all production zones of the Pacific Northwest. It has early maturity, very good adult resistance to stripe rust, shorter height with very good straw strength, good test weight, Hessian fly resistance, aluminum tolerance, and excellent yield potential in low, intermediate, high rainfall, and irrigated production areas. Ryan uniquely packages early maturity, top-end yield potential, and yield protection traits compared to soft white spring wheat varieties including Whit, B...

A prism array based portable microplate reader

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:49 GMT

Unmet Need: Portable and low-cost point-of-care smart phone readerTraditionally, microplate based assays rely on laboratory microplate reader for data reading and analysis. This greatly limited the application of microplate based assays to laboratories and well-trained professionals. For on-field applications that require rapid and immediate, low-cost, and accurate analysis, traditional method cannot meet these needs outside the laboratory. A portable and low-cost microplate reader is in demand for point-of-care (POC) and mobile health (mHealth), in-field applications, and low resource areas.&...

Mitigation of whisker growth in electroplated tin coatings by alloying with Indium

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:47 GMT

AbstractWe have demonstrated that an electroplated tin coating containing a small amount of indium leads to a total elimination of tin-whisker formation. Because of the small amount of indium involved, this breakthrough whisker-elimination approach proffers a cost-effective, lead-free tin-plating approach for electronics packaging applications that require Level II or Level III reliability (i.e., high to very-high reliability and/or lifetime). We are currently forming partnerships for the development and manufacture of commercial electroplating baths and expect these to become commercially ava...

Hybrid Nanoflowers for Bioassay

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:46 GMT

Researchers at Washington State University’s School of Mechanical and Materials Engineering have developed new approaches to increase the sensitivity of sandwich-type immunoreactions by 1000-fold and allow the visualization and quantification of target pathogens through color intensity detection. These approaches can be developed as universal signal amplification techniques and applied to the detection of a myriad of pathogens and protein biomarkers. The researchers have developed a three-in-one nanocomposite as a novel enzyme-labeled antibody which can be easily synthesized in a on...

Wheat Variety 'Resilience CL+' (WA8187), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:41 GMT

Resilience CL+ is a soft white common winter two-gene Imidazolinone tolerant (ClearfieldTM) wheat variety developed and released in 2016 by the Agricultural Research Center of Washington State University. Compared to the single-gene, the two-gene technology provides significantly better tolerance to Imidazolinone group of herbicide imazamox. Resilience CL+ was developed using marker-assisted background selection approach. Compared to popular wheat varieties including that with ClearfieldTM technology, Resilience CL+ has higher yield potential, excellent stripe rust resistance and foot ro...

Protein-based Nanofabrics as Multi-functional “Green” Air Filtering Materials for High Efficiency Particulate and Toxic Chemical Filtration

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:39 GMT

AbstractAir filters currently in the market cannot simultaneously purify the air from particles and chemicals effectively. The non-degradable synthetic nature of existing products also creates environmental issues. To solve these problems, researchers at Washington State University have developed a green multi-functional air filter. This filter is comprised of biodegradable materials and has been shown to not only filter particulate material out of the air, but also remove malicious toxic chemicals. This innovation is unique to the marketplace because it is comprised of biomaterials and ...

Fracture-Directed Steerable Needles

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:38 GMT

Challenge: Current steerable needle designs rely on beveled needle tips to determine the direction of tissue fracture. Reliance on on interactions between the tissue and needle bevel type inherently brings the inhomogeneity of tissues into question, and makes actualization of a desired bend across a range of tissues difficult. In addition, current designs only allow a 12-20cm radius of curvature of the needle. This uncertainty of bending and low actualization of curvature is hindering potential medical needle applications. Technology: This novel steerable nee...

A Two-Phase Approach for Time-Domain Ion Mobility Mass Spectrometry

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:35 GMT

SummaryDrift-tube ion mobility spectrometry (DT-IMS) is largely unmatched in its ability to rapidly screen passengers, cargo, and the surrounding environment for narcotics, explosives, and chemical warfare agents. However, DT-IMS are limited by duty cycle. Most experiments are on the order of < 1%, and this limitation impacts sensitivity. In addition, existing Fourier transform (FT) IMS cannot fully realize multiplexing gains, due to the need for two physical ion gates and most importantly, the need for apodization function to recover IMS spectra from raw frequency-encoded ion signals. More...

Methacrylated Vanillyl Alcohol as a Monomer and Reactive Diluent for Thermoset Polymers

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:32 GMT

Unsaturated polyester resins (UPR) and vinyl ester resins (VER) are widely usedthermosetting polymers for fiber reinforced composites. The global UPR market isapproximately a 5,000 kilo ton business and is experiencing continued growth. Theseresins typically are mixed with styrene (in amounts up to 50%) as a reactive diluentbefore being cured by a free radical polymerization. Styrene however, has significantdisadvantages owing to health, safety, and environmental concerns. The Clean Air Act Amendments of 1990 lists styrene as a hazardous air pollutant andoccupational exposure to styrene i...

Electrochemical Scaffold for Wound Healing

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:31 GMT

This technology establishes a novel foundation as an alternative to antibiotic-free wound dressings to eliminate infectious species from tissue via the continuous delivery of hydrogen peroxide (H2O2). Considerable attention is being focused on alternative, antibiotic-free biofilm removal strategies and the concept of electrical stimulation as a wound treatment has been advocated for over a century. While electrochemically-generated hydrogen peroxide near biofilm surfaces could potentially eliminate the biofilm, this requires continuous delivery at low concentrations in clinical settings. Our t...

Power Supply Modulators with Voltage and Frequency Partitioning

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:29 GMT

Abstract:Efficiency improvements of power amplifiers in wireless communication devices. Envelope tracking is a popular technique to improve efficiency of power amplifiers in current 4G LTE communication systems. However, next-generation wireless communications will feature ultra-high bandwidth, such as 250 MHz, to support the increasing demand for higher data rate. Existing envelope tracking supply modulators cannot support such high bandwidth, and extending the bandwidth of supply modulators results in significant loss of efficiency. This invention describes ultra-high...

Data-Driven Activity Prediction

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:28 GMT

Unmet Need: Simple and reliable approach to activity predictionAn individual’s activities affect that individual, society, and the environment. Over the past decade, maturing of data mining and pervasive computing technologies have made it possible to automate activity learning from sensor data. To observe and understand individuals' activities and their effects, and predict activities that will occur in future, baseline methods exist, but are not reliable and accurate. The Technology: Activity predictor in a prompting applicationThis invention describes an Activity Predictor...

Network-on-Chip (NoC) Systems with Wireless Interconnects

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:26 GMT

Abstract:This is an enabling technology to design energy efficient and high bandwidth multicore architectures with improved thermal profile over conventional wireline. Evaluation yielded lower latency and energy dissipation compared to a conventional wireline mesh. Network-on-chip (NoC) or network-on-a-chip is a communication subsystem on an integrated circuit (IC), typically between cores in a system on a chip (SoC). NoC technology applies networking theory and methods to on-chip communication and brings notable improvements over conventional bus and crossbar interconnection...

Behavioral Assessment within Smart Homes using Activity Curves

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:25 GMT

Challenge: Longitudinal assessment outside clinical environment Traditional individual behavioral health studies require a controlled laboratory or clinical environment distinct from an individual's usual living space. This can be costly, induce artificial stress on vulnerable subjects, and impact observed behavior. The Technology: Environmental sensor-based cognitive assessment This demonstrated method and implementation provides an alternative or additional tool for unobtrusive activity-based behavior and wellbeing monitoring, using data from pervasive computing and...

A low-cost super-stretchable optical strain sensors

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:22 GMT

Abstract Researchers at the WSU have produced a low cost alternative of a ubiquitously utilized stain sensor. The Fiber Bragg grating was first introduced in the late 1970’s, sense then the method has been shown to be effective and reliable as a strain sensor. Most conventional optical fiber strain sensors have complicated manufacturing processes and are limited to small-strain sensing (<5%). This novel innovation relates to producing high quality Fiber Bragg strain sensors at a low cost. The highly elastic and extensible fiber allows for a long period grating fiber, whic...

Self-Operable Non-Invasive Fully-Automated Biomedical Device for Vital Signs Monitoring

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:19 GMT

AbstractAccording to the Centers for Disease Control and Prevention, an average of 600,000 people die of heart disease in the U.S. every year (1 in every 4 deaths). Similar statistics are present globally, where about 35 percent of deaths are due to cardiovascular diseases. More than half of those deaths occurred in a hospital emergency room or before the patient reached the hospital. Many lives can be saved by providing patients and doctors with cardiovascular activity data; however, the current process is cumbersome to patients and time consuming to doctors. Researchers at WSU have deve...

Barley Variety 'Havener' (09WA265.5), Two-row Spring Barley

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:16 GMT

Havener is a two-row, hulless, spring food barley developed by the Agricultural Research Center of Washington State University. Havener is named in honor of Robert and Elizabeth Havener, long- time champions in the effort to eradicate hunger and malnutrition worldwide. Havener, developed specifically for human consumption, contains 50 to 75% higher β-glucan (a heart-healthy soluble dietary fiber) than common Washington-grown varieties Lyon, Muir, Champion, Bob and Baronesse. Havener has higher yields and test weights across all eastern Washington rainfall zones than the hulless...

Wheat Variety 'Melba' (WA8193), Soft White Spring Club Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:14 GMT

Melba is intended as a replacement for JD club spring wheat in intermediate, high rainfall, and irrigated production areas of the Pacific Northwest. Melba has similar maturity as JD, with shorter plant height, lower protein content, excellent resistance to stripe rust, very good test weight, and superior yield potential in intermediate, high rainfall, and irrigated production areas. Like JD, Melba is susceptible to Hessian fly. Melba is broadly adapted and has performed well in all production regions in the PNW.

Wheat Variety 'Jasper' (WA8169), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:12 GMT

Jasper, (WA8169) is a soft white winter wheat developed and released in 2014 by the Agricultural Research Center of Washington State University. Jasper is named after the first wheat breeder at WSU, William Jasper Spillman, and is the 100th release from WSU. Jasper provides a combination of excellent yield potential, great end-use quality, and good disease resistance for many production regions of the inland Pacific Northwest. Jasper is broadly adapted to many dryland and irrigated areas in the states of Washington and Idaho, and has maintained high yield potential across locations ...

Wheat Variety 'Seahawk' (WA8162), Soft White Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:09 GMT

Seahawk uniquely packages outstanding defense traits and very good yield potential—a winning combination. Seahawk is nearly immune to stripe rust based on a combination of seedling and adult plant resistance genes and holds-up without fungicide application under the most severe epidemics. Seahawk genetics are mainly based on Whit and Alpowa backgrounds—proven across the PNW over the past 20 years. Hessian fly resistance, superior test weight, very good aluminum tolerance, Fusarium head scab tolerance, shorter plant height with good straw strength, and very good-to-excell...

Wheat Variety 'Chet' (WA8165), Hard Red Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:07 GMT

Chet, a tall hard red spring wheat from Washington State University, is our best variety option for low-rainfall areas of eastern Washington and Oregon. Chet has very good adult plant stripe rust resistance, Hessian fly resistance, excellent test weight, very good aluminum tolerance, tall plant height with good straw strength, and very good-to-excellent yield potential across low rainfall areas of the PNW. Chet should replace Hollis and Kelse acres in low rainfall areas due to superior yield, test weight, protein content, and stripe rust resistance.

Wheat Variety 'Alum' (WA8166), Hard Red Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:04 GMT

Alum, a newly released hard red spring wheat from Washington State University, is intended to provide growers with low soil pH and aluminum toxicity; a very solid and broadly adapted hard red spring wheat variety. Alum has very good adult plant stripe rust resistance, Hessian fly resistance, above average test weight, very good aluminum tolerance, medium plant height with good straw strength, and very good-to-excellent yield potential across the PNW. Alum should be of particular interest to growers in Spokane, eastern Whitman, Columbia, and Walla Walla counties in Washington, and in...

Printed Three-Dimensional (3D) Passive Integrated Circuit (IC) Components

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:02 GMT

Challenge: Traditional IC manufacturing methods require separately manufactured components, limiting efficiency in manufacture and size.Technology Abstract: Printed 3D IC passive component architectures, nano-powder inks and composite material used to make them, and the associated direct-write manufacturing methods with jetting of nano-powder inks. This invention enables critical system level integration, compaction, and components with reduced parasitics. Applications and Advantages: Enables low parasitic components and system level compaction by 3-D components.Benefit...

Stretch-able Metallic Interconnects

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:16:00 GMT

AbstractThis invention comprises a novel architecture for thin or thick-film circuitry on a flexible or soft or stretch-able substrate composed of metallic elastic-plastic highly ductile materials, which enables the circuitry to sustain significant strains without breaking, and yet adhere to the substrate while it is stretched, bent, twisted or otherwise deformed.Flexible electronics are critical to a host of internet-ready devices including wearable sensing, biometric and communication devices, implants, roll-to-roll manufactured panels, etc. Flexible electronics are at the heart ...

3D Printed Flexible Antennas

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:58 GMT

Abstract:Method to create three dimensional sub-mm wavelength, and sub-THz frequency antennas on flexible and in-situ cured dielectric material along with directly printed metallic antenna elements over the dielectric. The three dimensional sub-mm wavelength antennas have applications in wearable flexible electronics as well as ultra-high speed chip-to-chip communication. Reliable antenna designs with three dimensional curved geometries can provide significant area/volume compaction and directionality to the signal propagation. Applica...

Underactuated, Tendon-Driven End-Effector for a Robotic Apple Harvester

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:56 GMT

AbstractApple picking is very labor intensive and expensive. Between 15-18 billion apples are harvested every year in Washington state alone for fresh market consumption, but often farmers can’t find enough people to pick the fruit. Furthermore, laborers are hard to acquire as apple picking is seasonal. This presents an urgent need for improved harvesting techniques. Apples require a system that is delicate enough to pick the fruit without bruising it, while also maneuvering around tree branches, leaves and other obstructions. Apple-picking robots can potentially save the apple industry ...

Barley Variety 'Muir' (07WA-601.6), Two-row Spring Barley

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:52 GMT

Muir is a two-row spring feed barley developed by the Agricultural Research Center of Washington State University. Muir is named in honor of Carl Muir, a former graduate student of Orville Vogel and a long-time field supervisor with the WSU Barley Breeding Program. Muir is a high yielding variety adapted to low to intermediate rainfall zones of the Palouse. Muir provides an excellent multi-disease resistance package, has reliably plump kernels and high protein, and performs well in low-input and organic systems.

Barley Variety 'Lyon' (05WA-316.K), Two-row Spring Barley

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:50 GMT

Lyon is a two-row dual-purpose malt and feed barley developed by the Agricultural Research Center of Washington State University. Lyon is named in honor of Steven R. Lyon, a farmer and long-time wheat researcher at Washington State University. Lyon is a high yielding, broadly adapted variety particularly well suited to intermediate and high rainfall zones of the Palouse where Bob, Baronesse, Lenetah, and Champion are currently being grown. Lyon has excellent stem rust resistance, high protein, and plump kernels across a wide range of environments.

Novel agents for smoking and tobacco cessation

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:47 GMT

AbstractNicotine is the molecule responsible for the psychopharmacological effects and the addictive properties of tobacco use and cigarette smoking. Researchers at Washington State University have developed an orally-available nicotine derivative that can be prescribed for the cessation of cigarette smoking and tobacco use. It specifically inhibits the major nicotine-metabolizing enzyme in the body and in some cases, another enzyme important in alternative nicotine metabolism. When administered in cigarette smokers and tobacco users, these agents will inhibit enzymes, resulting in...

Wheat Variety 'Mela CL+' (WA8155), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:42 GMT

Mela CL+ is a soft white common winter two-gene Imidazolinone tolerant (Clearfield) wheat variety developed and released in 2013 by the Agricultural Research Center of Washington State University. It’s the second two-gene Clearfield (CL+) wheat variety released by WSU. Compared to the single-gene Clearfield, the two-gene technology provides significantly better tolerance to Imidazolinone group of herbicide imazamox. Mela CL+ was developed using marker-assisted background selection approach. Compared to popular wheat varieties including those with Clearfield technology, Mela CL...

Wheat Variety 'Curiosity CL+' (WA8143), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:40 GMT

Curiosity CL+ is a soft white common winter two-gene Imidazolinone tolerant (Clearfield) wheat variety developed and released in 2013 by the Agricultural Research Center of Washington State University. It’s the first two-gene Clearfield (CL+) wheat variety released by WSU. Compared to the single-gene, the two-gene technology provides significantly better tolerance to Imidazolinone group of herbicide imazamox. Curiosity CL+ was developed using marker-assisted background selection approach. Compared to popular wheat varieties including those with Clearfield technology, Curiosity...

Low Power Local Oscillator Distribution and Phase Shifting Circuits

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:38 GMT

Abstract:Wireless communication devices often require incoming high frequency radio signals to be shifted and converted from analog prior to digital processing. This demands high power use, and circuits are sensitive to effects of parasitic capacitance. This patented technology offers improved performance and includes a sub-harmonic injection-locked local oscillator (SILO), which may be configured for mm-wave with coupled phase shifter, matching filter, resonance tank, and transformer-coupled oscillator.Applications and advantages:Lower power consumption facilitates high data rates...

Performance Analysis of Power Grid Monitors

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:33 GMT

Abstract: WSU has developed and continues to research tools for power grid management by generation and distribution system operators, to increase electrical security, reliability, and resilience. Power management tools rely on continued accuracy of distributed monitoring equipment. This invention includes systems and methods to test and analyze accuracy of power grid monitors (e.g., phasor measurement units (PMUs)). Includes comparison of time-stamped monitor and reference data and capable of operating in various steady state and dynamic grid conditions. Ap...

Control of plant fatty acid biosynthesis pathways through controlled degradation of selected target proteins

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:31 GMT

Researchers at Washington State University have discovered a novel regulatory mechanism, which notonly significantly increases seed oil production in seeds of plants, but can also improve plant stresstolerance as well as modify a broad range of other developmental aspects. The approach focuses on modifying the ability of a group of proteins called BPMs to recognize and triggerthe degradation of a wide range of substrate proteins. These substrate proteins are differenttranscription factors and each one is responsible for regulating developmental aspects such as root andshoot growth, flower...

Apple harvesting machine for formally trained orchards

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:30 GMT

Unmet Need: Improved mechanical harvesting techniques for apples and other specialty crop orchardsHarvesting labor accounts for 50% of the total tree fruit production cost and this is expected to continue to rise as labor shortages increase. This presents an urgent need for improved mechanical harvesting techniques in apple and other specialty crop orchards. In addition, growers are adopting new horticulture practices that allow for tree limbs to be trellised to a post or wire because, among other benefits, these trellised systems will be ideal for automated and mechanized harvesting technique...

Wheat Variety 'Puma' (WA8134), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:27 GMT

Puma, (WA8134) is a soft white winter wheat developed and released in 2013 by the Agricultural Research Center of Washington State University. Puma provides a combination of excellent yield potential, test weight, end-use quality, and disease resistance for intermediate to high rainfall dryland winter wheat production areas of the inland Pacific Northwest. Puma is best adapted to regions of Washington, Idaho, and Oregon where Madsen, Brundage 96, WB-528 and Tubbs 06 are currently under production. Puma has a unique disease resistant package for areas where low pH, Cephalosporium str...

Detection of androgen-independent prostate cancer progression and resultant treatment

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:24 GMT

Unmet Need: Reliable biomarker and therapeutic targets for androgen-independent prostate cancerProstate cancer (PC) is the second most common cause of cancer related deaths in men in the United States. PC is initially androgen-dependent, making androgen deprivation therapy (ADT) the first line of defense in combating the disease. Though this treatment initially reduces tumor size, almost all patients eventually develop androgen-independent prostate cancer (AIPC), which is resistant to this primary form of therapy and is ultimately lethal.The Technology: Late stage prostate cancer diagnostic an...

Power Grid Voltage Stability Monitoring

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:20 GMT

Abstract:Grid management ensures voltage stability and resilience upon disturbance. Earlier iterative tools could not provide real-time calculations. RT-VSMAP Engine: Real Time Voltage Stability Monitoring and Prediction allows for more proactive management of electric power systems. This tested technology provides continuous analysis of system topology and measurement inputs, such as synchrophasor data from phasor measurement units (PMUs) and phasor data concentrators (PDCs), supervisory control and data acquisition (SCADA) facilities, and other sensors. Applications an...

A NATURAL ANTIMICROBIAL TO CONTROL PATHOGENIC E. COLI

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:11 GMT

AbstractHarmful strains of Escherichia coli bacteria, primarily found in cattle cause severe, sometimes life-threatening human illness. According to the US Centers for Disease Control and Prevention, an estimated 110,000 cases (due to specifically enterohaemorrhagic E. coli (EHEC)) occur annually in the United States, and is now plaguing more than 30 countries around the globe. The other E. coli virotype, enterotoxigenic E. coli (ETEC), according to the World Health Organization, causes more than 200 million cases of diarrhea and 380,000 deaths, mostly in children in developing countries.A tea...

Wheat Variety 'Glee' (WA8074), Hard Red Spring Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:08 GMT

Glee, is a hard red spring wheat developed by the Agricultural Research Center of Washington State University. Glee was named in honor of Virginia Gale Lee, an inspiring graduate student in the WSU Spring Wheat Breeding program who died from a rare, aggressive form of cancer in 2010. Glee provides a combination of high yield potential and excellent disease resistance in dryland spring wheat production areas of the inland Pacific Northwest. Glee’s five-year yield average is significantly higher than all comparison hard red spring varieties in WSU Variety Testing Trials from 12&...

Wheat Variety 'Otto' (WA8092), Soft White Winter Wheat

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:15:04 GMT

Otto, is a soft white common wheat developed and released in 2011 by the Agricultural Research Center of Washington State University. Otto was named in honor of Otto Amen, a former state representative, WSU alumnus, and wheat producer who established an endowment to fund dryland wheat research in Washington. Otto provides a combination of excellent yield potential and excellent disease resistance in dryland winter wheat production areas of the inland Pacific Northwest. Otto is best adapted to regions of Washington, Idaho, and Oregon where Eltan, Bruehl, and Xerpha are currently grow...

Chemical Ligation

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:57 GMT

Researchers at Washington State University Department of Chemistry have invented an improved method of native chemical ligation. The method involves the ligation of a peptide thioacid with an aziridinyl peptide to yield an aziridinyl peptide ligation product without the use ofprotecting groups. Ring opening of the ligation product ultimately yields the linearized peptide. Advantages:This method does not require the presence of a cysteinyl peptide for the reaction to occur and thus, it is not limited to proteins that contain or can tolerate the presence of a cysteine residue This meth...

Use of Photosynthetic Pigment Stabilizing Chemicals to Regulate Ripening and Quality in All Fruits and Vegetables

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:56 GMT

Abstract 1-Methylcyclopropene (1-MCP) is used in various agricultural commodities to slow the ripening process of fruit while in storage and therefore extend their shelf life. MCP sometimes works in pears and sometimes does not, because pears oftentimes never resume ripening. Studies on d'Anjou pears, for example, showed that pears could be kept immature (maintaining the brix and firmness levels) on a post-harvest basis by spraying them with a particular organic compound. Initial studies on Bartlett pear, sprayed post-harvest, showed similar results. The benefits of spraying with the organic c...

Aeration/Lime-Addition for Solids and Phosphorus Removal from Anaerobic Digested Effluent

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:50 GMT

AbstractLivestock confinement facilities generate large amounts of animal waste that can create serious environmental and human health concerns. For example, animal waste constituents such as organic matter, nitrogen, phosphorus, pathogens and metals can degrade water quality, air quality, and adversely impact human health. Organic matter, for example, contains a high amount of biodegradable organics and when discharged to surface waters will compete for, and deplete the limited amount of dissolved oxygen available, causing fish to die and other undesirable impacts. Similarly, nutrient loading...

Power Systems Global Voltage Security Assessment

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:48 GMT

Abstract: WSU has developed and continues to research tools for power grid management by generation and distribution system operators, to increase electrical security, reliability, and resilience. Beyond the traditional voltage security assessment methods like V-P curve and Q-V curve, this invention provides a fast computation method based on power flow to indicate a global voltage security assessment index. Built on the understanding of line sensitivity, this kind of index is able to describe the current system operation status and mark the weakest bus for remediation. Applica...

Cardiac Biomarker Sensing Based on Nanofluidic Amplification and Resonant Optical Detection

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:47 GMT

Abstract This invention relates to a compact, lab-on-a-chip sensor platform to detect multiple cardiac biomarkers from microliter bloods samples. Optical characterization of cardiac biomarkers in will lay the groundwork for development of novel optical devices for detection and analysis of biomedically important molecules important for disease diagnosis. This platform integrates sample preprocessing through a nanofluidic field effect transistor (FET) electrofocusing unit with resonant optical detection based on silicon microrings. The combination of immunoaffinity-based re...

Anti-Microbial Silver-Doped Stainless Steel Implants/Nails

cascadeherriott@wsu.edu — Wed, 27 Oct 2021 16:14:43 GMT

Abstract For many years silver has been used as a broad spectrum antimicrobial agent, applied towards reducing infections of burn victims, water treatment, treating textiles, among others. With an increasing amount of antibiotic-resistant bacteria, the utility of silver coatings and treatments are again being recognized as a cost- effective way to prevent bacterial infections such as for medical implants. This is especially crucial when surgeries are performed in environments where sanitation is not ensured. This WSU invention relates to the use of silver coatings on medical imp...

Long-lasting discrete sacrificial anodes for corrosion mitigation in chloride contaminated concrete

cascadeherriott@wsu.edu — Tue, 26 Jan 2021 13:15:36 GMT

Unmet Need: Long-lasting commercial discrete sacrificial anode (DSA) products Corrosion of reinforcement materials induced by chloride contamination in concrete is a leading cause of structural damage and premature degradation in reinforced concrete (RC) structures, with significant implications for safety, reliability, economics, and environmental performance. Discrete sacrificial anodes (DSAs) are one tool used for corrosion mitigation of steel reinforcements in chloride contaminated concrete. Recent studies reveal that commercially available DSA products have shorter service life than ex...

Test MP

cascadeherriott@wsu.edu — Thu, 10 Sep 2020 15:32:36 GMT

some stuff for a product.